ELISA SAMD8 Antibody, HRP

Quantity :50µg Clone Number: Aliases:SAMD8Sphingomyelin synthase-related protein 1 antibody; SMSr antibody; EC 2.7.8.- antibody; Ceramide phosphoethanolamine synthase antibody; CPE synthase antibody; Sterile alpha motif domain-containing protein 8 antibody; SAM domain-containing protein 8 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q96LT4 Immunogen:Recombinant Sphingomyelin synthase-related protein 1 protein (1-152AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Sphingomyelin synthases syntheQuantity sphingolipids throµgh transfer of a phosphatidyl head group on to the primary hydroxyl of ceramide. SAMD8 is an endoplasmic reticµLum (ER) transferase that has no sphingomyelin synthase activity but can convert phosphatidylethanolamine (PE) and ceramide to ceramide phosphoethanolamine (CPE) albeit with low product yield. Appears to operate as a ceramide sensor to control ceramide homeostasis in the endoplasmic reticµLum rather than a converter of ceramides. Seems to be critical for the integrity of the early secretory pathway. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SAMD8 Research Areas:Cancer; Cell biology; Metabolism; Signal transduction