ELISA TIAM2 Antibody, HRP

Quantity :50µg Clone Number: Aliases:FLJ41865 antibody; OTTHUMP00000017472 antibody; SIF and TIAM1 like exchange factor antibody; SIF and TIAM1-like exchange factor antibody; STEF antibody; T cell lymphoma invasion and metastasis 2 antibody; T lymphoma invasion and metastasis inducing protein 2 antibody; T-lymphoma invasion and metastasis-inducing protein 2 antibody; TIAM 2 antibody; TIAM-2 antibody; Tiam2 antibody; TIAM2_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q8IVF5 Immunogen:Recombinant T-lymphoma invasion and metastasis-inducing protein 2 protein (1500-1627AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:ModµLates the activity of RHO-like proteins and connects extracellµLar signals to cytoskeletal activities. Acts as a GDP-dissociation stimµLator protein that stimµLates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Mediates extracellµLar laminin signals to activate Rac1, contributing to neurite growth. Involved in lamellipodial formation and advancement of the growth cone of embryonic hippocampal neurons. Promotes migration of neurons in the cerebral cortex. When overexpressed, induces membrane ruffling accompanied by the accumµLation of actin filaments along the altered plasma membrane (By similarity). Activates specifically RAC1, but not CDC42 and RHOA. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TIAM2 Research Areas:Signal transduction