ELISA FAM20C Antibody, HRP

Quantity :50µg Clone Number: Aliases:C76981 antibody; Dentin matrix protein 4 antibody; DKFZp547C074 antibody; DMP-4 antibody; DMP4 antibody; DMP4_ antibody; ExtracellµLar serine/threonine protein kinase Fam20C antibody; Fam20c antibody; Family with sequence similarity 20 member C antibody; GEF CK antibody; Golgi enriched fraction casein kinase antibody; Protein FAM20C antibody; RNS antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q8IXL6 Immunogen:Recombinant ExtracellµLar serine/threonine protein kinase FAM20C protein (107-224AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Golgi serine/threonine protein kinase that phosphorylates secretory pathway proteins within Ser-x-Glu/pSer motifs and plays a key role in biomineralization of bones and teeth (PubMed:22582013, PubMed:23754375, PubMed:25789606). Constitutes the main protein kinase for extracellµLar proteins, generating the majority of the extracellµLar phosphoproteome (PubMed:26091039). Mainly phosphorylates proteins within the Ser-x-Glu/pSer motif, but also displays a broader substrate specificity (PubMed:26091039). Phosphorylates casein as well as a number of proteins involved in biomineralization such as AMELX, AMTN, ENAM and SPP1 (PubMed:22582013, PubMed:25789606). In addition to its role in biomineralization, also plays a role in lipid homeostasis, wound healing and cell migration and adhesion (PubMed:26091039). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:FAM20C Research Areas:Developmental biology; Signal transduction; Stem cells