ELISA ZC3HC1 anti-

Quantity :50µL Clone Number: Aliases:hNIPA antibody; NIPA_ antibody; Nuclear interacting partner of ALK antibody; Nuclear interacting partner of anaplastic lymphoma kinase antibody; Nuclear-interacting partner of ALK antibody; Nuclear-interacting partner of anaplastic lymphoma kinase antibody; zc3hc1 antibody; Zinc finger C3HC type containing 1 antibody; Zinc finger C3HC-type protein 1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q86WB0 Immunogen:Recombinant Nuclear-interacting partner of ALK protein (1-260AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB; Recommended dilution: WB:1:1000-1:5000 Background:Essential component of an SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regµLates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation resµLts in nuclear accumµLation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ZC3HC1 Research Areas:Cell biology