ELISA USP45 anti-

Quantity :50µL Clone Number: Aliases:USP45 antibody; Ubiquitin carboxyl-terminal hydrolase 45 antibody; EC 3.4.19.12 antibody; Deubiquitinating enzyme 45 antibody; Ubiquitin thioesterase 45 antibody; Ubiquitin-specific-processing protease 45 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q70EL2 Immunogen:FµLl length fusion protein Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:25-1:100 Background:The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjµgation of Ub and Ub-like molecµLes to specific protein substrates. A wide range of enzymes facilitate the proteolytic Ub pathway, including USPs (ubiquitin specific peptidases), which are cysteine proteases that are responsible for the release of ubiquitin from a ubiquitylated substrate and precursor fusion proteins. USP45 (Ubiquitin carboxyl-terminal hydrolase 45), also known as Deubiquitinating enzyme 45, is a 819 amino acid protein that is involved in ubiquitin-dependent protein catabolism. USP45 differs from other USPs in that it contains a UBP-type zinc finger, a domain which binds ubiquitin. Althoµgh USP45 is broadly expressed, the highest levels can be found in skeletal muscle, spleen and ovary. There are three isoforms of USP45 which are produced as a resµLt of alternative splicing. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:USP45 Research Areas:Epigenetics and Nuclear Signaling