ELISA SMG6 anti-

Quantity :50µg Clone Number: Aliases:SMG6 antibody; C17orf31 antibody; EST1A antibody; KIAA0732Telomerase-binding protein EST1A antibody; EC 3.1.-.- antibody; EST1-like protein A antibody; Ever shorter telomeres 1A antibody; Smg-6 homolog antibody; Telomerase subunit EST1A antibody; hSmg5/7a antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q86US8 Immunogen:Recombinant Telomerase-binding protein EST1A protein (251-511AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200 Background:Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini. May have a general role in telomere regµLation. Promotes in vitro the ability of TERT to elongate telomeres. Overexpression induces telomere uncapping, chromosomal end-to-end fusions (telomeric DNA persists at the fusion points) and did not perturb TRF2 telomeric localization. Binds to the single-stranded 5\'-(GTGTGG)(4)GTGT-3\' telomeric DNA, but not to a telomerase RNA template component (TER). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SMG6 Research Areas:Cancer