ELISA PAN2 Antibody, FITC

Quantity :50µg Clone Number: Aliases:hPan2 antibody; Inactive ubiquitin carboxyl terminal hydrolase 52 antibody; Inactive ubiquitin carboxyl-terminal hydrolase 52 antibody; KIAA0710 antibody; PAB dependent poly(A) specific ribonuclease subunit 2 antibody; PAB-dependent poly(A)-specific ribonuclease subunit 2 antibody; PABP dependent poly(A) nuclease 2 antibody; PAN 2 antibody; PAN2 antibody; PAN2 homolog PABP1 dependent poly A specific ribonuclease subunit antibody; PAN2 poly(A) specific ribonuclease subunit homolog antibody; PAN2 polyA specific ribonuclease subunit homolog antibody; PAN2_ antibody; Ubiquitin specific peptidase 52 antibody; Ubiquitin specific protease 52 antibody; USP 52 antibody; USP52 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q504Q3 Immunogen:Recombinant PAB-dependent poly(A)-specific ribonuclease subunit PAN2 protein (628-908AA) Raised in:Rabbit Reactivity: Tested Applications: Background:Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA when the poly(A) stretch is bound by poly(A)-binding protein (PABP), which is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3\\\'-5\\\' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5\\\'-3\\\' exonucleolytic degradation by XRN1. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:FITC Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PAN2 Research Areas:Epigenetics and Nuclear Signaling