ELISA USP2 anti-

Quantity :50µL Clone Number: Aliases:41 kDa ubiquitin specific protease antibody; 41 kDa ubiquitin-specific protease antibody; Deubiquitinating enzyme 2 antibody; Ubiquitin carboxyl terminal hydrolase 2 antibody; Ubiquitin carboxyl-terminal hydrolase 2 antibody; ubiquitin specific peptidase 2 antibody; Ubiquitin specific processing protease 2 antibody; Ubiquitin specific protease 12 antibody; Ubiquitin specific protease 9 antibody; Ubiquitin specific protease, 41kD antibody; Ubiquitin thioesterase 2 antibody; Ubiquitin thiolesterase 2 antibody; Ubiquitin-specific-processing protease 2 antibody; Ubiquitin-specific-processing protease testis antibody; UBP-t antibody; UBP2_ antibody; UBP41 antibody; USP2 antibody; USP9 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O75604 Immunogen:Fusion protein of USP2 Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:25-1:100 Background:This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regµLators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. MµLtiple alternatively spliced transcript variants encoding different isoforms have been identified. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:USP2 Research Areas:Epigenetics and Nuclear Signaling;Cell biology