ELISA SOCS1 anti-

Quantity :50µL Clone Number: Aliases:CISH 1 antibody; CISH1 antibody; Cytokine inducible SH2 protein 1 antibody; JAB antibody; JAK binding protein antibody; JAK-binding protein antibody; Janus kinase binding protein antibody; SOCS 1 antibody; SOCS-1 antibody; Socs1 antibody; SOCS1_ antibody; SSI 1 antibody; SSI-1 antibody; SSI1 antibody; STAT induced STAT inhibitor 1 antibody; STAT-induced STAT inhibitor 1 antibody; Suppressor of cytokine signaling 1 antibody; Supressor of cytokine signalling 1 antibody; TEC interacting protein 3 antibody; Tec-interacting protein 3 antibody; TIP 3 antibody; TIP-3 antibody; TIP3 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O15524 Immunogen:Synthetic peptide of SOCS1 Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:50-1:200 Background:This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regµLators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice sµggested the role of this gene as a modµLator of IFN-gamma action, which is required for normal postnatal growth and survival. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SOCS1 Research Areas:Epigenetics and Nuclear Signaling;Immunology;Signal transduction