ELISA SNX17 Antibody, HRP

Quantity :50µg Clone Number: Aliases:Similar to a putative C elegans gene encoded in cosmid F17H10 antibody; Snx17 antibody; SNX17_ antibody; Sorting nexin 17 antibody; Sorting nexin-17 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q15036 Immunogen:Recombinant Sorting nexin-17 protein (280-457AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Critical regµLator of endosomal recycling of numerous receptors, channels, and other transmembrane proteins. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Plays a role in the sorting of endocytosed LRP1 and APP, and prevents their degradation. Required for maintenance of normal cell surface levels of APP and LRP1. Recycles internalized integrins ITGB1, ITGB5 and their associated alpha subunits, preventing them from lysosomal degradation. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SNX17 Research Areas:Signal transduction