ELISA SEMA5A Antibody, HRP

Quantity :50µg Clone Number: Aliases:SEMA5A antibody; SEMAF antibody; Semaphorin-5A antibody; Semaphorin-F antibody; Sema F antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q13591 Immunogen:Recombinant Semaphorin-5A protein (201-400AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Bifunctional axonal guidance cue regµLated by sµLfated proteoglycans; attractive effects resµLt from interactions with heparan sµLfate proteoglycans (HSPGs), while the inhibitory effects depend on interactions with chondroitin sµLfate proteoglycans (CSPGs). Ligand for receptor PLXNB3. In glioma cells, SEMA5A stimµLation of PLXNB3 resµLts in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellµLar collapse as well as inhibition of cell migration and invasion throµgh ARHGDIA-mediated inactivation of RAC1. May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SEMA5A Research Areas:Others