ELISA TTI1 anti-

Quantity :50µL Clone Number: Aliases:TELO2 interacting protein 1 Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O43156 Immunogen:Synthetic peptide of TTI1 Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:25-1:100 Background:RegµLator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellµLar resistance to DNA damage stresses, like ionizing radiation (IR), µLtraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly syntheQuantityd PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regµLate cell growth and survival in response to nutrient and hormonal signals. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TTI1 Research Areas:Epigenetics and Nuclear Signaling;Cell biology