ELISA VDR (Ab-51) anti-

Quantity :100µL Clone Number: Aliases:1 25 dihydroxyvitamin D3 receptor antibody; 1 antibody; 1,25 dihydroxyvitamin D3 receptor antibody; 1,25-@dihydroxyvitamin D3 receptor antibody; 25-dihydroxyvitamin D3 receptor antibody; Member 1 antibody; NR1I1 antibody; Nuclear receptor subfamily 1 group I member 1 antibody; PPP1R163 antibody; Protein phosphatase 1, regµLatory subunit 163 antibody; VDR antibody; VDR_ antibody; Vitamin D (1,25- dihydroxyvitamin D3) receptor antibody; Vitamin D hormone receptor antibody; Vitamin D nuclear receptor variant 1 antibody; Vitamin D receptor antibody; Vitamin D3 receptor antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P11473 Immunogen:SyntheQuantityd non-phosphopeptide derived from Vitamin D3 Receptor around the phosphorylation site of serine 51 (R-R-S(p)-M-K). Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. RegµLates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis. Baker A.R., Proc. Natl. Acad. Sci. U.S.A. 85:3294-3298(1988). Goto H., Biochim. Biophys. Acta 1132:103-108(1992). Miyamoto K., Mol. Endocrinol. 11:1165-1179(1997). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:VDR Research Areas:Epigenetics and Nuclear Signaling;Cancer;Signal transduction