ELISA CLPS anti-

Quantity :50µL Clone Number: Aliases:clpS antibody; COL_ antibody; Colipase antibody; Colipase pancreatic antibody; Pancreatic colipase preproprotein antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P04118 Immunogen:Fusion protein of CLPS Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200 Background:The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, sµggesting regµLation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CLPS Research Areas:Cancer?CardiovascµLar;Metabolism;Signal transduction