ELISA RIN1 anti-

Quantity :100µL Clone Number: Aliases:RIN1 antibody; Ras and Rab interactor 1 antibody; Ras inhibitor JC99 antibody; Ras interaction/interference protein 1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q13671 Immunogen:SyntheQuantityd peptide derived from internal of RIN1. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Ras effector protein, which may serve as an inhibitory modµLator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regµLate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis. Colicelli J., Proc. Natl. Acad. Sci. U.S.A. 88:2913-2917(1991). Han L., Mol. Cell. Biol. 15:1318-1323(1995). Han L., Proc. Natl. Acad. Sci. U.S.A. 94:4954-4959(1997) Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:RIN1 Research Areas:Epigenetics and Nuclear Signaling?Neuroscience?Cancer;Signal transduction