ELISA SESN1 anti-

Quantity :50µL Clone Number: Aliases:1110002G11Rik antibody; AU044290 antibody; MGC118148 antibody; MGC138241 antibody; MGC142129 antibody; OTTMUSP00000022799 antibody; p53 activated gene 26 antibody; p53 regµLated PA26 nuclear protein antibody; p53 regµLated protein PA26 antibody; p53-regµLated protein PA26 antibody; PA26 antibody; RP11-787I22.1 antibody; sesn1 antibody; SESN1_ antibody; SEST1 antibody; sestrin 1 antibody; Sestrin-1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9Y6P5 Immunogen:Synthetic peptide of SESN1 Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB; ELISA:1:1000-1:2000, WB:1:200-1:1000 Background:This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellµLar response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which resµLts in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SESN1 Research Areas:Cell biology;Metabolism