ELISA PDE9A Antibody, Biotin

Quantity :50µg Clone Number: Aliases:5''-cyclic phosphodiesterase 9A antibody; cGMP specific 3' 5' cyclic phosphodiesterase type 9 antibody; FLJ90181 antibody; High affinity cGMP-specific 3'' antibody; High-affinity cGMP-specific 3'5'-cyclic phosphodiesterase 9A antibody; HSPDE9A2 antibody; OTTHUMP00000109399 antibody; PDE 9A antibody; Pde9a antibody; PDE9A_ antibody; Phosphodiesterase 9A antibody; phosphodiesterase PDE9A21 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O76083 Immunogen:Recombinant High affinity cGMP-specific 3\',5\'-cyclic phosphodiesterase 9A protein (426-533AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Specifically hydrolyzes the second messenger cGMP, which is a key regµLator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP (PubMed:9624146, PubMed:18757755, PubMed:21483814). Specifically regµLates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regµLator of cardiac hypertrophy in myocytes and muscle. Does not regµLate nitric oxide-dependent cGMP in heart (PubMed:25799991). Additional experiments are required to confirm whether its ability to hydrolyze natriuretic-peptide-dependent cGMP is specific to heart or is a general feature of the protein (Probable). In brain, involved in cognitive function, such as learning and long-term memory (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PDE9A Research Areas:Signal transduction