ELISA RTCA Antibody, HRP

Quantity :50µg Clone Number: Aliases:RTCA antibody; RPC antibody; RPC1 antibody; RTC1 antibody; RTCD1 antibody; RNA 3'-terminal phosphate cyclase antibody; RNA cyclase antibody; RNA-3'-phosphate cyclase antibody; EC 6.5.1.4 antibody; RNA terminal phosphate cyclase domain-containing protein 1 antibody; RTC domain-containing protein 1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O00442 Immunogen:Recombinant RNA 3\'-terminal phosphate cyclase protein (167-379AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Catalyzes the conversion of 3\'-phosphate to a 2\',3\'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3\'P to produce RNA-N3\'PP5\'A; (C) and attack of the adjacent 2\'-hydroxyl on the 3\'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellµLar RNA processing. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:RTCA Research Areas:Others