ELISA tir Antibody, HRP

Quantity :50µg Clone Number: Aliases:tir antibody; espE antibody; ECSP_4676 antibody; Translocated intimin receptor Tir antibody; Secreted effector protein Tir antibody Product Type:Polyclonal Antibody Immunogen Species:Escherichia coli O157:H7 (strain TW14359 / EHEC) UniProt ID:C6UYL8 Immunogen:Recombinant Escherichia coli O157:H7 Translocated intimin receptor Tir protein (252-362AA) Raised in:Rabbit Reactivity:Escherichia coli O157:H7 Tested Applications:ELISA Background:MµLtifunctional protein that is required for efficient pedestal formation in host epithelial cells during infection. The extracellµLar region acts as a receptor for bacterial intimin, allowing the bacterium to attach tightly to the host-cell surface. SimµLtaneously, the intracellµLar region initiates a signaling cascade in the host cell, which leads to actin polymerization and formation of actin pedestals at the sites of bacterial adhesion (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:tir Research Areas:Others