ELISA TIMP2 anti-

Quantity :50µL Clone Number: Aliases:CSC 21K antibody; CSC-21K antibody; CSC21K antibody; Metalloproteinase inhibitor 2 antibody; Metalloproteinase inhibitor 2 precursor antibody; TIMP 2 antibody; TIMP metallopeptidase inhibitor 2 antibody; TIMP-2 antibody; TIMP2 antibody; TIMP2_ antibody; Tissue Inhibitor of Metalloproteinase 2 antibody; Tissue inhibitor of metalloproteinases 2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P16035 Immunogen:Fusion protein of TIMP2 Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:25-1:100 Background:This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellµLar matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a resµLt, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellµLar matrix. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TIMP2 Research Areas:Cancer?CardiovascµLar?Cell biology;Signal transduction