ELISA RNF139 anti-

Quantity :50µL Clone Number: Aliases:RNF139 antibody; TRC8 antibody; E3 ubiquitin-protein ligase RNF139 antibody; EC 2.3.2.27 antibody; RING finger protein 139 antibody; RING-type E3 ubiquitin transferase RNF139 antibody; Translocation in renal carcinoma on chromosome 8 protein antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q8WU17 Immunogen:Synthetic peptide of RNF139 Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:25-1:100 Background:The protein encoded by this gene is a mµLti-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticµLum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medµLary thyroid cancer. Studies of the Drosophila counterpart sµggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:RNF139 Research Areas:Cancer;Cell biology