ELISA SENP3 anti-

Quantity :100µL Clone Number: Aliases:SENP3 antibody; SENP3_ antibody; Sentrin / SUMO specific protease 3 antibody; Sentrin specific protease 3 antibody; Sentrin-specific protease 3 antibody; Sentrin/SUMO-specific protease SENP3 antibody; SMT3IP1 antibody; SSP3 antibody; SUMO 1 specific protease 3 antibody; SUMO-1-specific protease 3 antibody; SUMO1 specific protease 3 antibody; SUMO1/sentrin/SMT3 specific peptidase 3 antibody; SUSP3 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9H4L4 Immunogen:SyntheQuantityd peptide derived from Internal of SENP3. Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100 Background:Protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjµgates. Deconjµgates SUMO2 from MEF2D, which increases its transcriptional activation capability. Deconjµgates SUMO2 and SUMO3 from CDCA8. Redox sensor that, when redistributed into nucleoplasm, can act as an effector to enhance HIF1A transcriptional activity by desumoylating EP300. Required for rRNA processing throµgh deconjµgation of SUMO2 and SUMO3 from nucleophosmin, NPM1. Plays a role in the regµLation of sumoylation status of ZNF148. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes. Yeh E.T.H., Gene 248:1-14(2000). Choi S.J., Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases. Wiemann S., Genome Res. 11:422-435(2001). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SENP3 Research Areas:Cell biology