ELISA IGF1R (Ab-1346) anti-

Quantity :100µL Clone Number: Aliases:CD221 antibody; CD221 antigen antibody; IGF 1 receptor antibody; IGF 1R antibody; IGF I receptor antibody; IGF-I receptor antibody; Igf1r antibody; IGF1R_ antibody; IGFIR antibody; IGFIRC antibody; IGFR antibody; InsµLin like growth factor 1 receptor antibody; InsµLin like growth factor 1 receptor precursor antibody; InsµLin-like growth factor 1 receptor beta chain antibody; InsµLin-like growth factor I receptor antibody; JTK13 antibody; MGC142170 antibody; MGC142172 antibody; MGC18216 antibody; Soluble IGF1R variant 1 antibody; Soluble IGF1R variant 2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P08069 Immunogen:Peptide sequence around aa.1344~1348 (Q-P-Y-A-H) derived from IGF-1R Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC; WB:1:500-1:1000, IHC:1:50-1:200 Background:This receptor binds insµLin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimµLated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1. Adams, T.E. et al. (2000) Cell. Mol. Life Sci. 57, 1050-1093 Baserga, R. et al. (2000) Oncogene 19, 5574-5581 Scheidegger, K.J. et al. (2000) J. Biol. Chem. 275, 38921-38928. O'Connor R, et al. Mol Cell Biol 1997 Jan; 17(1): 427-35 Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. Conjµgate:Non-conjµgated Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:IGF1R Research Areas:Cancer;Developmental biology;Signal transduction