ELISA Phospho-ELK1 (Ser389) anti-

Quantity :100µL Clone Number: Aliases:ELK 1 antibody; Elk1 antibody; ELK1 member of ETS oncogene family antibody; ELK1 protein antibody; ELK1; ETS transcription factor antibody; ELK1_ antibody; ELK2 member of ETS oncogene family antibody; ETS domain containing protein Elk 1 antibody; ETS domain containing protein Elk1 antibody; ETS domain protein Elk1 antibody; ETS domain-containing protein Elk-1 antibody; ETS like gene 1 antibody; Member of ETS oncogene family antibody; Oncogene Elk1 antibody; Tyrosine kinase (ELK1) oncogene antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P19419 Immunogen:Peptide sequence around phosphorylation site of serine 389 (P-R-S(p)-P-A) derived from Elk-1. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC; WB:1:500-1:1000, IHC:1:50-1:100 Background: Elk-1 is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. Alternatively spliced transcript variants encoding the same protein have been found for this gene Janknecht R, et al. (1993) EMBO J. 12(13): 5097-5104. Marais R, et al. (1993) Cell 73:381-393. Kortenjann M, et al. (1994) Mol Cell Biol. 14:4815-4824. Hill C S, et al. (1995) Cell. 80:199-211. Cavigelli M, et al. (1995) EMBO J. 14:5957-5964. Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjµgate:Non-conjµgated Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ELK1 Research Areas:Epigenetics and Nuclear Signaling;Cancer;Signal transduction