ELISA TNFRSF1B anti-

Quantity :50µL Clone Number: Aliases:CD120b antibody; p75 antibody; p75 TNF receptor antibody; p75TNFR antibody; p80 TNF alpha receptor antibody; p80 TNF-alpha receptor antibody; Soluble TNFR1B variant 1 antibody; TBP-2 antibody; TBPII antibody; TNF R II antibody; TNF R2 antibody; TNF R75 antibody; TNF-R2 antibody; TNF-RII antibody; TNFBR antibody; TNFR-II antibody; TNFR1B antibody; TNFR2 antibody; TNFR80 antibody; TNFRII antibody; Tnfrsf1b antibody; TNR1B_ antibody; Tumor necrosis factor beta receptor antibody; Tumor necrosis factor binding protein 2 antibody; Tumor necrosis factor receptor 2 antibody; Tumor necrosis factor receptor superfamily member 1B antibody; Tumor necrosis factor receptor type II antibody; Tumor necrosis factor-binding protein 2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P20333 Immunogen:Fusion protein of TNFRSF1B Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:5-1:20 Background:The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thoµght to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also sµggest a role of this protein in protecting neurons from apoptosis by stimµLating antioxidative pathways. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TNFRSF1B Research Areas:Cancer;Cell biology;Immunology;Signal transduction