ELISA SMG7 anti-

Quantity :100µL Clone Number: Aliases:breast cancer-associated antigen SGA-56M antibody; C1orf16 antibody; EST1 like protein C antibody; EST1 telomerase component homolog C antibody; EST1-like protein C antibody; EST1C antibody; ever shorter telomeres 1C antibody; FLJ23717 antibody; hSMG-7 antibody; nonsense mediated mRNA decay factor (C. elegans) antibody; Protein SMG7 antibody; SGA56M antibody; SMG 7 antibody; SMG-7 homolog antibody; Smg7 antibody; SMG7_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q92540 Immunogen:SyntheQuantityd peptide derived from internal of SMG7. Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB, IF; WB:1:500-1:3000, IF:1:100-1:500 Background:Plays a role in nonsense-mediated mRNA decay. Recruits UPF1 to cytoplasmic mRNA decay bodies. Together with SMG5 is thoµght to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation. Ohnishi T., Mol. Cell 12:1187-1200(2003). Nagase T., DNA Res. 3:321-329(1996). Nakajima D., DNA Res. 9:99-106(2002). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SMG7 Research Areas:Epigenetics and Nuclear Signaling