ELISA MAN1B1 anti-

Quantity :100µL Clone Number: Aliases:MAN1B1 antibody; UNQ747/PRO1477Endoplasmic reticµLum mannosyl-oligosaccharide 1,2-alpha-mannosidase antibody; EC 3.2.1.113 antibody; ER alpha-1,2-mannosidase antibody; ER mannosidase 1 antibody; ERMan1 antibody; Man9GlcNAc2-specific-processing alpha-mannosidase antibody; Mannosidase alpha class 1B member 1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9UKM7 Immunogen:SyntheQuantityd peptide derived from internal of MAN1B1. Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single alpha-1,2-linked mannose residue from Man9GlcNAc2 to produce Man8GlcNAc2, but at high enzyme concentrations, as found in the ER quality control compartment (ERQC), it further trims the carbohydrates to Man5-6GlcNAc2. Tremblay L.O., Glycobiology 9:1073-1078(1999) [PubMed: 10521544]. Gonzalez D.S., J. Biol. Chem. 274:21375-21386(1999) [PubMed: 10409699]. Clark H.F., Genome Res. 13:2265-2270(2003) [PubMed: 12975309]. Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:MAN1B1 Research Areas:Tags & Cell Markers