ELISA UBE2T anti-

Quantity :100µL Clone Number: Aliases:Cell proliferation inducing gene 50 protein antibody; Cell proliferation-inducing gene 50 protein antibody; HSPC150 antibody; HSPC150 protein similar to ubiquitin conjµgating enzyme antibody; PIG50 antibody; Ube2t antibody; UBE2T_ antibody; Ubiquitin carrier protein T antibody; Ubiquitin conjµgating enzyme antibody; ubiquitin conjµgating enzyme E2 T antibody; Ubiquitin conjµgating enzyme E2T antibody; Ubiquitin protein ligase T antibody; Ubiquitin-conjµgating enzyme E2 T antibody; Ubiquitin-protein ligase T antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9NPD8 Immunogen:SyntheQuantityd peptide derived from internal of UBE2T. Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in mitomycin-C (MMC)-induced DNA repair: acts as a specific E2 ubiquitin-conjµgating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCL and FANCI. May contribute to ubiquitination and degradation of BRCA1. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11'-, 'Lys-27'-, 'Lys-48'- and 'Lys-63'-linked polyubiquitination. Okaze H., Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases. Hu R.-M., Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000). Zhang Q.-H., Genome Res. 10:1546-1560(2000). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:UBE2T Research Areas:Epigenetics and Nuclear Signaling;Cell biology