ELISA ST5 anti-

Quantity :100µL Clone Number: Aliases:DENND2B antibody; DENN domain containing protein 2B antibody; DENN domain-containing protein 2B antibody; DENN/MADD domain containing 2B antibody; HeLa tumor suppression 1 antibody; HTS1 antibody; p126 antibody; ST 5 antibody; ST5 antibody; ST5_ antibody; Suppression of tumorigenicity 5 antibody; Suppression of tumorigenicity 5 protein antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P78524 Immunogen:SyntheQuantityd peptide derived from internal of ST5. Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May be involved in cytoskeletal organization and tumorogenicity. Isoform 1 seems to be involved in a signaling transduction pathway leading to activation of MAPK1/ERK2. Isoform 3 may block ERK2 activation stimµLated by ABL1. Isoform 3 may alter cell morphology and cell growth. Lichy J.H., Nucleic Acids Res. 24:4700-4708(1996). Amid C., Cytogenet. Cell Genet. 93:284-290(2001). Lichy J.H., Cell Growth Differ. 3:541-548(1992). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ST5 Research Areas:Cancer;Signal transduction