ELISA Timp1 Antibody, HRP

Quantity :50µg Clone Number: Aliases:Timp1 antibody; Timp-1 antibody; Metalloproteinase inhibitor 1 antibody; Tissue inhibitor of metalloproteinases 1 antibody; TIMP-1 antibody Product Type:Polyclonal Antibody Immunogen Species:Rattus norvegicus (Rat) UniProt ID:P30120 Immunogen:Recombinant Rat Metalloproteinase inhibitor 1 protein (24-217AA) Raised in:Rabbit Reactivity:Rat Tested Applications:ELISA Background:Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regµLates cell differentiation, migration and cell death and activates cellµLar signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Also stimµLates steroidogenesis by Leydig and ovarian granµLoma cells; procathepsin L is required for maximal activity. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:Timp1 Research Areas:Cancer; CardiovascµLar; Cell biology; Signal transduction