ELISA STK40 anti-

Quantity :50µL Clone Number: Aliases:STK40 antibody; SGK495 antibody; SHIK antibody; Serine/threonine-protein kinase 40 antibody; EC 2.7.11.1 antibody; SINK-homologous serine/threonine-protein kinase antibody; Sµgen kinase 495 antibody; SgK495 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q8N2I9 Immunogen:Fusion protein of STK40 Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, IHC; ELISA:1:1000-1:5000, IHC:1:50-1:200 Background:STK40 (Serine/threonine-protein kinase 40), also known as Sµgen kinase 495, is a 435 amino acid protein kinase that may be a negative regµLator of NF?B and p53-mediated gene expression. Localized to both the cytoplasm and the nucleus, STK40 is ubiquitously expressed. STK40 has a central serine/threonine protein kinase domain and is homologous to TRB-3, a protein that regµLates activation of MAP kinases and inhibits NF?B-mediated gene transcription. Similarly, overexpression of STK40 inhibits NF?B activation triggered by TNF and also inhibits p53-mediated transcription. There are four named isoforms of STK40 that are produced as a resµLt of alternative splicing. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:STK40 Research Areas:Epigenetics and Nuclear Signaling;Cell biology;Signal transduction