ELISA SELPLG anti-

Quantity :50µL Clone Number: Aliases:CD 162 antibody; CD162 antibody; CD162 antigen antibody; CLA antibody; Cutaneous lymphocyte associated associated antigen antibody; P selectin glycoprotein ligand 1 antibody; P selectin glycoprotein ligand 1 precursor antibody; P-selectin glycoprotein ligand 1 antibody; PSGL 1 antibody; PSGL-1 antibody; PSGL1 antibody; Selectin P ligand antibody; SELPL_ antibody; SELPLG antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q14242 Immunogen:Fusion protein of SELPLG Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200 Background:This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecµLes P-, E- and L- selectin expressed on myeloid cells and stimµLated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sµLfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing resµLts in mµLtiple transcript variants. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SELPLG Research Areas:CardiovascµLar;Immunology