ELISA TNF anti-

Quantity :100µL Clone Number: Aliases:APC1 antibody; APC1 protein antibody; Cachectin antibody; DIF antibody; Differentiation inducing factor antibody; Macrophage cytotoxic factor antibody; Tnf antibody; TNF superfamily member 2 antibody; TNF superfamily, member 2 antibody; TNF, macrophage derived antibody; TNF, monocyte derived antibody; TNF-a antibody; TNF-alpha antibody; TNFA antibody; TNFA_ antibody; TNFSF2 antibody; Tumor necrosis factor (TNF superfamily member 2) antibody; Tumor necrosis factor alpha antibody; Tumor necrosis factor antibody; Tumor necrosis factor ligand superfamily member 2 antibody; Tumor Necrosis Factor, Membrane Form antibody; Tumor necrosis factor, soluble form antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P01375 Immunogen:SyntheQuantityd peptide derived from internal of TNFA. Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, IHC, IF; IHC:1:50-1:100, IF:1:100-1:500 Background:Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimµLation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimµLate cell proliferation and induce cell differentiation. The TNF intracellµLar domain (ICD) form induces IL12 production in dendritic cells. Neville M.J., J. Immunol. 162:4745-4754(1999). Xie T., Genome Res. 13:2621-2636(2003). Kim Y.J., Hum. Mol. Genet. 12:2541-2546(2003). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TNF Research Areas:Cancer?CardiovascµLar;Immunology?Metabolism;Signal transduction