ELISA PSME3 Antibody, HRP

Quantity :50µg Clone Number: Aliases:11S regµLator complex gamma subunit antibody; 11S regµLator complex subunit gamma antibody; Activator of mµLticatalytic protease subunit 3 antibody; Ki antibody; Ki antigen antibody; Ki nuclear autoantigen antibody; Ki, PA28 gamma antibody; PA28 gamma antibody; PA28g antibody; PA28gamma antibody; Proteasome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki) antibody; Proteasome (prosome, macropain) activator subunit 3 antibody; Proteasome activator 28 gamma antibody; Proteasome activator 28 subunit gamma antibody; Proteasome activator complex subunit 3 antibody; Proteasome activator subunit 3 antibody; PSME3 antibody; PSME3_ antibody; REG GAMMA antibody; REG-gamma antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P61289 Immunogen:Recombinant Proteasome activator complex subunit 3 protein (2-252AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regµLator, a doµghnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumµLation and resµLting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regµLation. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PSME3 Research Areas:Cancer; Cell biology; Immunology