ELISA SHB anti-

Quantity :100µL Clone Number: Aliases:bA3J10.2 antibody; OTTHUMP00000021397 antibody; RP11 3J10.8 antibody; RP113J10.8 antibody; SH2 domain containing adapter protein B antibody; SH2 domain-containing adapter protein B antibody; SHB (Src homology 2 domain containing) adaptor protein B antibody; SHB adaptor protein (a Src homology 2 protein) antibody; SHB adaptor protein antibody; Shb antibody; SHB_ antibody; Src homology 2 domain containing adaptor protein B antibody; Src homology 2 protein antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q15464 Immunogen:SyntheQuantityd peptide derived from C-terminal of SHB. Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Adapter protein which regµLates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regµLating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. May also regµLate IRS1 and IRS2 signaling in insµLin-producing cells. Welsh M., Oncogene 9:19-27(1994). Humphray S.J., Nature 429:369-374(2004). Mural R.J., Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SHB Research Areas:Developmental biology;Signal transduction?Stem cells