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ELISA TAF1 anti-

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Quantity :100µL Clone Number: Aliases:BA2R antibody; CCG1 antibody; CCGS antibody; Cell cycle G1 phase defect antibody; Cell cycle gene 1 protein antibody; Complementation of cell cycle block G1 to S antibody; DYT3 antibody; N TAF1 antibody; NSCL2 antibody; OF antibody; p250 antibody; TAF 1 antibody; TAF(II)250 antibody; TAF1 antibody; TAF1 RNA polymerase II TATA box binding protein (TBP) associated factor 250kDa antibody; TAF1_ antibody; TAF2A antibody; TAFII-250 antibody; TAFII250 antibody; TATA box binding protein (TBP) associated factor RNA polymerase II A 250kD antibody; TBP associated factor 250 kDa antibody; TBP-associated factor 250 kDa antibody; Transcription factor TFIID p250 polypeptide antibody; Transcription initiation factor TFIID 250 kDa subunit antibody; Transcription initiation factor TFIID subunit 1 antibody; XDP antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P21675 Immunogen:SyntheQuantityd peptide derived from internal of TAF1. Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, IHC; IHC:1:50-1:100 Background:Largest component and core scaffold of the TFIID basal transcription factor complex. Contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Phosphorylates TP53 on 'Thr-55' which leads to MDM2-mediated degradation of TP53. Phosphorylates GTF2A1 and GTF2F1 on Ser residues. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. Exhibits histone acetyltransferase activity towards histones H3 and H4. Sekiguchi T., Mol. Cell. Biol. 11:3317-3325(1991). Ruppert S., Nature 362:175-179(1993). Nolte D., Proc. Natl. Acad. Sci. U.S.A. 100:10347-10352(2003). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TAF1 Research Areas:Epigenetics and Nuclear Signaling

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