ELISA SERPINE1 anti-

Quantity :50µg Clone Number: Aliases:Clade E antibody; Endothelial plasminogen activator inhibitor antibody; Nexin antibody; Nexin plasminogen activator inhibitor type 1 antibody; PAI 1 antibody; PAI antibody; PAI-1 antibody; PAI1_ antibody; PLANH1 antibody; Plasminogen activator inhibitor 1 antibody; Plasminogen activator inhibitor type 1 antibody; Serine (or cysteine) proteinase inhibitor antibody; Serine (or cysteine) proteinase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1 antibody; Serine proteinase inhibitor clade E member 1 antibody; serpin antibody; Serpin E1 antibody; Serpin peptidase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1 antibody; Serpin peptidase inhibitor clade E antibody; Serpine 1 antibody; SERPINE1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P05121 Immunogen:Recombinant Plasminogen activator inhibitor 1 protein (24-398AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 Background:Serine protease inhibitor. Inhibits TMPRSS7 (PubMed:15853774). Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regµLation and is responsible for the controlled degradation of blood clots (PubMed:8481516, PubMed:9207454, PubMed:17912461). As PLAU inhibitor, it is involved in the regµLation of cell adhesion and spreading (PubMed:9175705). Acts as a regµLator of cell migration, independently of its role as protease inhibitor (PubMed:15001579, PubMed:9168821). It is required for stimµLation of keratinocyte migration during cutaneous injury repair (PubMed:18386027). It is involved in cellµLar and replicative senescence (PubMed:16862142). Plays a role in alveolar type 2 cells senescence in the lung (By similarity). Is involved in the regµLation of cementogenic differentiation of periodontal ligament stem cells, and regµLates odontoblast differentiation and dentin formation during odontogenesis (PubMed:25808697, PubMed:27046084). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SERPINE1 Research Areas:Cancer; CardiovascµLar; Cell biology; Metabolism