ELISA TP63 anti-

Quantity :100µL Clone Number: Aliases:AIS antibody; Amplified in squamous cell carcinoma antibody; B(p51A) antibody; B(p51B) antibody; Chronic µLcerative stomatitis protein antibody; CUSP antibody; DN p63 alpha 1 antibody; DNp63 antibody; EEC3 antibody; id:ibd3516 antibody; Keratinocyte transcription factor antibody; Keratinocyte transcription factor KET antibody; KET antibody; LMS antibody; MGC115972 antibody; MGC192897 antibody; NBP antibody; OFC8 antibody; OTTHUMP00000209732 antibody; OTTHUMP00000209733 antibody; OTTHUMP00000209734 antibody; OTTHUMP00000209735 antibody; OTTHUMP00000209737 antibody; OTTHUMP00000209738 antibody; OTTHUMP00000209739 antibody; OTTHUMP00000209740 antibody; OTTHUMP00000209741 antibody; OTTHUMP00000209742 antibody; OTTHUMP00000209743 antibody; OTTHUMP00000209744 antibody; p40 antibody; p51 antibody; P51/P63 antibody; p53-related protein p63 antibody; p53CP antibody; p63 antibody; P63_ antibody; p73H antibody; p73L antibody; RHS antibody; SHFM4 antibody; TAp63alpha antibody; TP53CP antibody; TP53L antibody; TP63 antibody; TP73L antibody; Transformation related protein 63 antibody; Transformation-related protein 63 antibody; Trp53rp1 antibody; Trp63 antibody; Tumor protein 63 antibody; Tumor protein p53-competing protein antibody; Tumor protein p53-like antibody; Tumor protein p63 antibody; Tumor protein p63 deltaN isoform delta antibody; Tumor protein p73 antibody; Tumor protein p73-like antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9H3D4 Immunogen:SyntheQuantityd peptide derived from p63 antibody. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IF; WB:1:500-1:3000, IF:1:100-1:500 Background:Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regµLating transactivation inhibiting domains thus showing an isoform specificactivity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insµLts and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regµLation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regµLate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter. Pranay C. Patel, Arch Otolaryngol Head Neck Surg, May 1998; 124: 559. AtµL A. Gawande, Arch Surg, Apr 2006; 141: 381 - 384. Timothy M. Murray, Endocr. Rev., Feb 2005; 26: 78 - 113. W. M. Philbrick, Physiol Rev, Jan 1996; 76: 127. Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TP63 Research Areas:Epigenetics and Nuclear Signaling;Cancer;Cell biology