ELISA PICK1 anti-

Quantity :50µg Clone Number: Aliases:dJ1039K5 antibody; MGC15204 antibody; OTTHUMP00000028509 antibody; PICK 1 antibody; Pick1 antibody; PICK1_ antibody; PRKCA binding protein antibody; PRKCA-binding protein antibody; PRKCABP antibody; Protein interacting with C kinase 1 antibody; Protein interacting with PRKCA antibody; Protein interacting with PRKCA 1 antibody; Protein kinase C alpha binding protein antibody; Protein kinase C-alpha-binding protein antibody; Protein that interacts with C kinase 1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9NRD5 Immunogen:Recombinant PRKCA-binding protein (1-200AA) Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200 Background:Probable adapter protein that bind to and organize the subcellµLar localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regµLating the trafficking and internalization of AMPA receptors. May be regµLated upon PRKCA activation. May regµLate ASIC1/ASIC3 channel. RegµLates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competetive with nucleation promoting factors and is linked to neuronal morphology regµLation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regµLation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regµLation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PICK1 Research Areas:Neuroscience; Signal transduction