ELISA Phospho-MDC1 (Ser513) anti-

Quantity :100µL Clone Number: Aliases:Homologue to Drosophila photoreceptor protein calphotin antibody; MDC 1 antibody; Mdc1 antibody; MDC1_ antibody; Mediation of DNA damage checkpoint 1 antibody; Mediator of DNA damage checkpoint 1 antibody; Mediator of DNA damage checkpoint protein 1 antibody; NFBD 1 antibody; NFBD1 antibody; Nuclear factor with BRCT domains 1 antibody; Nuclear Factor with BRCT Domains Protein 1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q14676 Immunogen:Peptide sequence around phosphorylation site of Serine 513(E-R-S(p)-Q-A) derived from MDC1. Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; IHC:1:50-1:100 Background: The MDC1 protein contains a forkhead homology-associated (FHA) domain and 2 BRCA1 (MIM 113705) C-terminal motifs (BRCTs) and is required for the intra-S-phase DNA damage checkpoint. Nagase T., DNA Res. 3:17-24(1996). Shiina T., Genetics 173:1555-1570(2006). Mungall A.J., Nature 425:805-811(2003). Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:MDC1 Research Areas:Epigenetics and Nuclear Signaling