ELISA ZNF281 anti-

Quantity :50µg Clone Number: Aliases:GC box binding zinc finger protein 1 antibody; GC-box-binding zinc finger protein 1 antibody; GZP1 antibody; Transcription factor ZBP-99 antibody; ZBP 99 antibody; ZBP99 antibody; zfp281 antibody; Zinc finger DNA binding protein 99 antibody; Zinc finger DNA-binding protein 99 antibody; Zinc finger protein 281 antibody; ZN281_ antibody; ZNF281 antibody; ZNP 99 antibody; ZNP 99 transcription factor antibody; ZNP99 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9Y2X9 Immunogen:Recombinant Zinc finger protein 281 protein (1-300AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200 Background:Transcription repressor that plays a role in regµLation of embryonic stem cells (ESCs) differentiation. Required for ESCs differentiation and acts by mediating autorepression of NANOG in ESCs: binds to the NANOG promoter and promotes association of NANOG protein to its own promoter and recruits the NuRD complex, which deacetylates histones. Not required for establishement and maintenance of ESCs. Represses the transcription of a number of genes including GAST, ODC1 and VIM. Binds to the G-rich box in the enhancer region of these genes. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ZNF281 Research Areas:Epigenetics and Nuclear Signaling; Developmental biology; Stem cells