ELISA UBE2L3 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:E2 F1 antibody; L UBC antibody; L-UBC antibody; UB2L3_ antibody; UBCE7 antibody; UbcH7 antibody; UbcM4 antibody; Ube2l3 antibody; Ubiquitin carrier protein L3 antibody; Ubiquitin conjµgating enzyme E2 L3 antibody; Ubiquitin protein ligase L3 antibody; Ubiquitin-conjµgating enzyme E2 L3 antibody; Ubiquitin-conjµgating enzyme E2-F1 antibody; Ubiquitin-protein ligase L3 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P68036 Immunogen:Recombinant Ubiquitin-conjµgating enzyme E2 L3 protein (1-154AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Ubiquitin-conjµgating enzyme E2 that specifically acts with HECT-type and RBR family E3 ubiquitin-protein ligases. Does not function with most RING-containing E3 ubiquitin-protein ligases because it lacks intrinsic E3-independent reactivity with lysine: in contrast, it has activity with the RBR family E3 enzymes, such as PARK2 and ARIH1, that function like function like RING-HECT hybrids. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes \'Lys-11\'-linked polyubiquitination. Involved in the selective degradation of short-lived and abnormal proteins. Down-regµLated during the S-phase it is involved in progression throµgh the cell cycle. RegµLates nuclear hormone receptors transcriptional activity. May play a role in myelopoiesis. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:UBE2L3 Research Areas:Epigenetics and Nuclear Signaling; Cell biology