ELISA UBASH3A Antibody, Biotin

Quantity :50µg Clone Number: Aliases:Cbl interacting protein 4 antibody; Cbl-interacting protein 4 antibody; CLIP4 antibody; STS 2 antibody; STS-2 antibody; Suppressor of T cell receptor signaling 2 antibody; Suppressor of T-cell receptor signaling 2 antibody; T cell ubiquitin ligand antibody; T cell ubiquitin ligand protein antibody; T-cell ubiquitin ligand 1 antibody; TµLA antibody; TµLA-1 antibody; UBASH3A antibody; ubiquitin associated and SH3 domain containing, A antibody; Ubiquitin-associated and SH3 domain-containing protein A antibody; UBS3A_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P57075 Immunogen:Recombinant Ubiquitin-associated and SH3 domain-containing protein A protein (287-455AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Interferes with CBL-mediated down-regµLation and degradation of receptor-type tyrosine kinases. Promotes accumµLation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface. Exhibits negligigle protein tyrosine phosphatase activity at neutral pH. May act as a dominant-negative regµLator of UBASH3B-dependent dephosphorylation. May inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:UBASH3A Research Areas:Cell biology