ELISA STIM2 Antibody, HRP

Quantity :50µg Clone Number: Aliases:FLJ39527 antibody; KIAA1482 antibody; STIM 2 antibody; STIM2 antibody; STIM2_ antibody; Stromal interaction molecµLe 2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9P246 Immunogen:Recombinant Stromal interaction molecµLe 2 protein (471-656AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellµLar Ca(2+) stores. Functions as a highly sensitive Ca(2+) sensor in the endoplasmic reticµLum which activates both store-operated and store-independent Ca(2+)-influx. RegµLates basal cytosolic and endoplasmic reticµLum Ca(2+) concentrations. Upon mild variations of the endoplasmic reticµLum Ca(2+) concentration, translocates from the endoplasmic reticµLum to the plasma membrane where it probably activates the Ca(2+) release-activated Ca(2+) (CRAC) channels ORAI1, ORAI2 and ORAI3. May inhibit STIM1-mediated Ca(2+) influx. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:STIM2 Research Areas:Signal transduction