ELISA SOX3 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:GHDX antibody; MRGH antibody; PHP antibody; PHPX antibody; sox3 antibody; SOX3_ antibody; SOXB antibody; SRY (sex determining region Y)-box 3 antibody; SRY Box 3 antibody; SRY-related HMG-box gene 3 antibody; Transcription factor Sox-3 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P41225 Immunogen:Recombinant Transcription factor SOX-3 protein (4-118AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Transcription factor required during the formation of the hypothalamo-pituitary axis. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. Required also within the pharyngeal epithelia for craniofacial morphogenesis. Controls a genetic switch in male development. Is necessary for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granµLosa cells (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SOX3 Research Areas:Epigenetics and Nuclear Signaling; Neuroscience; Signal transduction