ELISA SMARCA2 Antibody, HRP

Quantity :50µg Clone Number: Aliases:ATP dependent helicase SMARCA2 antibody; ATP-dependent helicase SMARCA2 antibody; BAF190 antibody; BAF190B antibody; BRG1-associated factor 190B antibody; BRM antibody; FLJ36757 antibody; Global transcription activator homologous sequence antibody; hBRM antibody; hSNF2a antibody; MGC74511 antibody; Possible global transcription activator SNF2L2 antibody; Probable global transcription activator SNF2L2 antibody; Protein brahma homolog antibody; SMARCA2 antibody; SMCA2_ antibody; SNF2 alpha antibody; SNF2 like 2 antibody; SNF2-alpha antibody; SNF2/SWI2 like protein 2 antibody; SNF2L2 antibody; SNF2LA antibody; Sth1p antibody; Sucrose nonfermenting 2 like protein 2 antibody; SWI/SNF related matrix associated actin dependent regµLator of chromatin subfamily A member 2 antibody; SWI/SNF-related matrix-associated actin-dependent regµLator of chromatin subfamily A member 2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P51531 Immunogen:Recombinant Probable global transcription activator SNF2L2 protein (700-1216AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. Also involved in vitamin D-coupled transcription regµLation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adµLt state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the mµLtipotent neural stem cells. The nBAF complex along with CREST plays a role regµLating the activity of genes essential for dendrite growth. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SMARCA2 Research Areas:Epigenetics and Nuclear Signaling