ELISA RBPJ Antibody, HRP

Quantity :50µg Clone Number: Aliases:AI843960 antibody; AOS3 antibody; CBF 1 antibody; CBF-1 antibody; CBF1 antibody; csl antibody; IGKJRB antibody; IGKJRB1 antibody; J kappa recombination signal binding protein antibody; J kappa-recombination signal-binding protein antibody; KBF2 antibody; NY REN 30 antigen antibody; RBP J antibody; RBP J kappa antibody; RBP JK antibody; RBP-J antibody; RBP-J kappa antibody; RBP-JK antibody; Rbpj antibody; RBPJK antibody; RBPSUH antibody; recombination signal binding protein for immunoglobµLin kappa J region antibody; Recombining binding protein suppressor of hairless antibody; Renal carcinoma antigen NY-REN-30 antibody; SUH antibody; SUH_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q06330 Immunogen:Recombinant Recombining binding protein suppressor of hairless protein (243-485AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Transcriptional regµLator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regµLates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellµLar domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobµLin kappa-type J segment recombination signal sequence. Binds specifically to methylated DNA. Binds to the oxygen responsive element of COX4I2 and activates its transcription under hypoxia conditions (4% oxygen) (PubMed:23303788). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:RBPJ Research Areas:Epigenetics and Nuclear Signaling; Neuroscience; Stem cells