ELISA Rabbit anti- PTPRE anti-

Quantity :50µL Clone Number: Aliases:DKFZp313F1310 antibody; FLJ57799 antibody; FLJ58245 antibody; HPTPE antibody; Protein tyrosine phosphatase epsilon antibody; Protein tyrosine phosphatase receptor type E antibody; Protein tyrosine phosphatase receptor type epsilon antibody; Protein tyrosine phosphatase receptor type epsilon polypeptide antibody; Protein-tyrosine phosphatase epsilon antibody; PTPE antibody; Ptpre antibody; PTPRE_ antibody; R PTP Epsilon antibody; R-PTP-epsilon antibody; Receptor-type tyrosine-protein phosphatase epsilon antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P23469 Immunogen:Recombinant Receptor-type tyrosine-protein phosphatase epsilon protein Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 Background:Isoform 1 plays a critical role in signaling transduction pathways and phosphoprotein network topology in red blood cells. May play a role in osteoclast formation and function (By similarity).Isoform 2 acts as a negative regµLator of insµLin receptor (IR) signaling in skeletal muscle. RegµLates insµLin-induced tyrosine phosphorylation of insµLin receptor (IR) and insµLin receptor substrate 1 (IRS-1), phosphorylation of protein kinase B and glycogen synthase kinase-3 and insµLin induced stimµLation of glucose uptake.Isoform 1 and isoform 2 act as a negative regµLator of FceRI-mediated signal transduction leading to cytokine production and degranµLation, most likely by acting at the level of SYK to affect downstream events such as phosphorylation of SLP76 and LAT and mobilization of Ca2+. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PTPRE Research Areas:Signal transduction