ELISA POLR3K Antibody, Biotin

Quantity :50µg Clone Number: Aliases:C11 antibody; C11 RNP3 antibody; DNA directed RNA polymerase III subunit K antibody; DNA directed RNA polymerase III subunit RPC10 antibody; DNA directed RNA polymerases III 12.5 kDa polypeptide antibody; DNA-directed RNA polymerase III subunit K antibody; DNA-directed RNA polymerase III subunit RPC10 antibody; hRPC11 antibody; HsC11p antibody; My010 antibody; POLR3K antibody; Polymerase (RNA) III (DNA directed) polypeptide K antibody; Polymerase (RNA) III (DNA directed) polypeptide K; 12.3 kDa antibody; RNA polymerase III 12.5 kDa subunit antibody; RNA polymerase III subunit (hRPC11) antibody; RNA polymerase III subunit C10 antibody; RNA polymerase III subunit C11 antibody; RNA polymerase III subunit CII antibody; RPC10 antibody; RPC10_ antibody; RPC11 antibody; RPC12.5 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9Y2Y1 Immunogen:Recombinant DNA-directed RNA polymerase III subunit RPC10 protein (1-108AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which syntheQuantitys small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellµLar bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B throµgh the RIG-I pathway. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:POLR3K Research Areas:Epigenetics and Nuclear Signaling