ELISA PLXNB2 anti-

Quantity :50µL Clone Number: Aliases:PLXNB2 antibody; KIAA0315 antibody; Plexin-B2 antibody; MM1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O15031 Immunogen:Recombinant Plexin-B2 protein (1080-1200AA) Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 Background:Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling. Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at \\\'Tyr-1248\\\'. Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development. RegµLates the migration of cerebellar granµLe cells in the developing brain. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May modµLate the activity of RAC1 and CDC42. Down-regµLates macrophage migration in wound-healing assays (in vitro) (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:PLXNB2 Research Areas:Others